Changes in plasma levels of 17-hydroxycorticosteroids during the intravenous administration of ACTH. I. A test of adrenocortical capacity in the human.

نویسندگان

  • K EIK-NES
  • A A SANDBERG
  • D H NELSON
  • F H TYLER
  • L T SAMUELS
چکیده

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منابع مشابه

The effect of intravenously-administered ACTH on plasma 17,21-dihydroxy-20-ketosteroids in normal individuals and in patients with disorders of the adrenal cortex.

The response of the adrenal cortex to exogenous ACTH has been recognized as one of the more specific and quantitative tests of adrenal function (1). Changes in the 24-hour excretion values of urinary 17-ketosteroids and 17-hydroxycorticosteroids during ACTH administration have proved to be valuable indices of adrenocortical capacity (2, 3). With the development of technics for the chemical esti...

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Free plasma 11-hydroxycorticosteroids in patients with adrenocortical disorders.

Free acid· fluorescent corticosteroids (11-0HCS) in plasma of patients with adrenocortical disorder was studied by the m ethod of De Moor. Differences in diurnal variations of 11-0HCS value were observed between healthy per s ons, pa tients with adenoma, and patients w ith hyperplasia of adr enals. Intravenous infus ion of cort icot ropin was efficient for the estimation of the adrenocortical f...

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Studies on the Mechanism of the Plasma 17-hydroxy- Corticosteroid Elevation Induced in Man

The administration of estrogens to man produces sustained elevation above normal levels of plasma 17-hydroxycorticosteroids (17-OHCS) (1, 2). The elevated levels of plasma 17-OHCS are associated with an augmented response of plasma levels of these steroids to exogenous adrenocorticotropic hormone (ACTH) and with a marked delay in the rate of clearance of exogenous cortisol from plasma (2). The ...

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Effects of eight-hour intravenous infusions of ACTH and the adrenocortical steroids in normal man. I. Basal gastric secretion, and plasma and urinary pepsinogen.

While there appears to be general agreement that adrenocortical deficiency results in a reduction of gastric secretory activity both in man (1-6) and in animals (7-11), no such unanimity of opinion exists regarding the effects of increased activity of the adrenal cortex on gastric secretion. Whereas some studies have shown that the administration of ACTH or of adrenocortical steroids may increa...

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Background: The aim of this study is comparing ACTH changes in epidural and intravenous analgesia technique after lower limb orthopedic surgery.Methods: In a randomized clinical trial in Hazrat Rasool  Akram Hospital during 1387-88 , 60 patients candidate for surgery on the lower extremities were randomly allocated to receive either postoperative analgesia  with epidural analgesia (PCEA) or IV ...

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 33 11  شماره 

صفحات  -

تاریخ انتشار 1954